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What Do Clinical Trial Endpoints Really Measure?A study investigates whether a commonly used clinical trial endpoint, progression-free survival, can be used to predict quality of life.
by Jon Kelvey
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Pushing the Immune System to Its LimitsImmunotherapy drugs have led to long-lasting remissions for some cancer patients with advanced disease. They also come with a new and diverse array of side effects.
by Kate Yandell
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Treating Breast Cancer in MenHormone therapy may lengthen life in men with hormone-related breast cancer, but this treatment is prescribed less frequently for men than for women.
by Marilyn Fenichel
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Forward Look
Endometrial Cancer Rates Rising in Many CountriesStudy findings suggest opportunities for preventing endometrial cancer.
by Deborah Abrams Kaplan
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2018 SABCS: Choosing the Right TreatmentStudies presented at the 2018 San Antonio Breast Cancer Symposium investigate when patients with early-stage breast cancer or precancerous breast conditions benefit from receiving less intense treatment.
by Kate Yandell
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Treating Cancer Based on Its Genetics, Not Its LocationMedical oncologist and sarcoma specialist George D. Demetri explains the significance of the recent approval of the oral drug Vitrakvi based on tumor genetics.
by Anna Azvolinsky
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From the Editor-in-Chief
DNA Profiling Moves From Forensics to DiagnosticsDNA profiling technologies are providing new ways to detect and monitor cancer.
by William G. Nelson, MD, PhD
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Forward Look
Banking on BacteriaResponse to immunotherapy may be linked to gut microbiome.
by Chris Palmer
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Forward Look
Improving Cancer Care in Sub-Saharan AfricaNew guidelines account for limited medical resources.
by Cameron Walker
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Forward Look
Treating Early-Stage Lung CancerEfforts are underway to define role of high-dose radiation.
by Stephen Ornes
Legislation to speed cancer drug development for children and adolescents requires drug companies to test drugs in children, but trials in people under 18 may take years to generate results.
by Marci A. Landsmann
Understanding Stress and CancerA symposium at the AACR Annual Meeting explores how social factors contribute to elevated risk of cancer in some populations.
by Eric Fitzsimmons
Exploring Amino Acids’ Impact on Tumor GrowthResearchers are investigating how to match specific dietary changes with therapy to impede cancer progression.
by Thomas Celona
Study Shows Minority Participation in Clinical Trials May Be DecliningResearcher speculates that costly genetic testing may be limiting outreach to underserved communities.
by Marci A. Landsmann
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Using Lymphocytes to Attack TumorsSooner rather than later may be the best strategy for using an experimental treatment for advanced melanoma.
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Closing Disparities Through Genetic TestingOlufunmilayo Olopade seeks widespread use of testing to encourage prevention and early detection of deadly cancers.
Learning Medicare’s ABCDs
