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  • What Is Tumor Mutational Burden?

    The Food and Drug Administration approved an immunotherapy drug for tumors with high tumor mutational burden regardless of tumor type. But some medical oncologists say it's not clear the biomarker is valid across all cancer types.

    by Anna Azvolinsky

  • From the Editor-in-Chief

    Cancer in Minority Populations

    Paying attention to the social determinants of health will promote greater equity in cancer outcomes for all.

    by William G. Nelson, MD, PhD

  • Taking Drug Dosing Off Autopilot

    Patient advocates with metastatic breast cancer argue that dosing of treatments for their disease should be more personalized and take into account quality of life.

    by Marcus A. Banks

  • More Choices to Treat Lung Cancer

    Advances in precision medicine and immunotherapy have led to better treatments for many patients with advanced lung cancer. But having a wider selection of therapies to choose from can make treatments more complex.

    by Kendall K. Morgan

  • Forward Look

    Creating More Inclusive Clinical Trials

    The Clinical Treatment Act aims to include more Medicaid recipients.

    by Jen Tota McGivney

  • Healthy Habits

    Ripe for the Picking

    Awareness of the link between cancer risk and a diet lacking fruits and vegetables has been declining.

    by Carisa D. Brewster

  • Forward Look

    Cancer Screening for the LGBTQ Community

    Fear of discrimination may lead to lower screening rates.

    by Tara Santora

  • Forward Look

    What’s Next

    A therapeutic vaccine targeting advanced cervical cancer.

    by Anna Azvolinsky

  • Targeted Therapy for Early-Stage Lung Cancer?

    A trial of the targeted therapy Tagrisso (osimertinib) for early-stage lung cancer finds that patients who take it go longer without having a cancer recurrence. Whether that should change clinical practice is under discussion.

    by Ashley P. Taylor

  • Worth the Wait

    Neoadjuvant therapy—using treatments such as chemotherapy, hormone therapy or radiation to shrink a tumor or treat unseen metastases before surgery—can improve outcomes for some patients.

    by Sharon Tregaskis